After his best friend dies in a racing accident, biking star Joe agrees to go back on the wheels for an exhibition in Chile. On a test run with his girlfriend Stephanie, they stumble upon a badly injured man dying from a mysterious virus. That's the start of a very bad day for them as they become the target of relentless killers ready to do anything to keep their secret to go out of the mountains.
Deeply upset by the passing of his best friend, a professional BMX rider accepts to partake in a race in Chile. Everything goes as planned until he stumbles upon a man who is infected by a mysterious virus and becomes the target of local assassins.